2021 Mercedes-Benz S-Class
13 trims available
2026
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1999
1998
1997
1996
1995
1994
1993
1992
AMG S65 Cabriolet, AMG S65 Cabriolet
from $109,800
3.8s
0-60
11.5s
1/4 Mile
621
HP
738
LB-FT
6.0L Twin-Turbo V12 ·
7-speed automatic ·
RWD
14 / 21 / 16 MPG ·
5,000 lbs
AMG S65 Coupe
from $109,800
3.8s
0-60
11.5s
1/4 Mile
621
HP
738
LB-FT
6.0L Twin-Turbo V12 ·
7-speed automatic ·
RWD
13 / 21 / 16 MPG ·
4,817 lbs
AMG S63 4MATIC+ Cabriolet
from $109,800
3.2s
0-60
11.1s
1/4 Mile
603
HP
664
LB-FT
4.0L Twin-Turbo V8 ·
9-speed automatic ·
AWD
15 / 24 / 18 MPG ·
4,949 lbs
AMG S63 4MATIC+ Coupe
from $109,800
3.3s
0-60
11.1s
1/4 Mile
603
HP
664
LB-FT
4.0L Twin-Turbo V8 ·
9-speed automatic ·
AWD
16 / 26 / 19 MPG ·
4,784 lbs
AMG S63 4MATIC+ Sedan
from $109,800
3.2s
0-60
11.3s
1/4 Mile
603
HP
664
LB-FT
4.0L Twin-Turbo V8 ·
9-speed automatic ·
AWD
17 / 26 / 20 MPG ·
4,784 lbs
EV Maybach S580 4MATIC
from $109,800
4.5s
0-60
12.8s
1/4 Mile
496
HP
516
LB-FT
Single Motor (15.0) ·
AWD
· 16 / 24 / 18 MPGe
EV S580 4MATIC Sedan
from $109,800
4.3s
0-60
12.4s
1/4 Mile
496
HP
516
LB-FT
Single Motor (15.0) ·
AWD
· 17 / 25 / 20 MPGe
NHTSA: ★★★★★
S560 4MATIC Coupe
from $109,800
4.3s
0-60
12.5s
1/4 Mile
463
HP
516
LB-FT
4.0L Twin-Turbo V8 ·
9-speed automatic ·
AWD
16 / 26 / 19 MPG ·
4,784 lbs
S560 Cabriolet
from $109,800
4.4s
0-60
12.6s
1/4 Mile
463
HP
516
LB-FT
4.0L Twin-Turbo V8 ·
9-speed automatic ·
RWD
17 / 24 / 19 MPG ·
4,872 lbs
S560 Coupe, S560 Coupe
from $109,800
4.3s
0-60
12.6s
1/4 Mile
463
HP
516
LB-FT
4.0L Twin-Turbo V8 ·
9-speed automatic ·
RWD
17 / 26 / 20 MPG ·
4,674 lbs
EV S500 4MATIC Sedan
from $109,800
4.7s
0-60
12.8s
1/4 Mile
429
HP
384
LB-FT
Single Motor (16.0) ·
AWD
· 21 / 30 / 24 MPGe
NHTSA: ★★★★★
All Trims Comparison
| Trim | 0-60 | 1/4 Mi | HP | Torque | Engine | Trans | Drive | MPG | Weight | MSRP |
|---|---|---|---|---|---|---|---|---|---|---|
| AMG S65 Cabriolet | 4.0s | 12.1s | 621 | 738 | 6.0L Twin-Turbo V12 | 7-speed automatic | RWD | 14 / 21 / 16 MPG | 5,000 lbs | $109,800 |
| AMG S65 Cabriolet | 4.0s | 12.1s | 621 | 738 | 6.0L Twin-Turbo V12 | 7-speed automatic | RWD | 14 / 21 / 16 MPG | 5,000 lbs | $109,800 |
| AMG S65 Coupe | 4.0s | 12.1s | 621 | 738 | 6.0L Twin-Turbo V12 | 7-speed automatic | RWD | 13 / 21 / 16 MPG | 4,817 lbs | $109,800 |
| AMG S63 4MATIC+ Cabriolet | 3.4s | 11.7s | 603 | 664 | 4.0L Twin-Turbo V8 | 9-speed automatic | AWD | 15 / 24 / 18 MPG | 4,949 lbs | $109,800 |
| AMG S63 4MATIC+ Coupe | 3.4s | 11.7s | 603 | 664 | 4.0L Twin-Turbo V8 | 9-speed automatic | AWD | 16 / 26 / 19 MPG | 4,784 lbs | $109,800 |
| AMG S63 4MATIC+ Sedan | 3.4s | 11.7s | 603 | 664 | 4.0L Twin-Turbo V8 | 9-speed automatic | AWD | 17 / 26 / 20 MPG | 4,784 lbs | $109,800 |
| Maybach S580 4MATIC | 4.7s | 13.2s | 496 | 516 | 4.0L Twin-Turbo V8 | 9-speed automatic | AWD | 16 / 24 / 18 MPGe | 5,247 lbs | $109,800 |
| S580 4MATIC Sedan | 4.4s | 12.8s | 496 | 516 | 4.0L Twin-Turbo V8 | 9-speed automatic | AWD | 17 / 25 / 20 MPGe | 4,850 lbs | $109,800 |
| S560 4MATIC Coupe | 4.5s | 13.0s | 463 | 516 | 4.0L Twin-Turbo V8 | 9-speed automatic | AWD | 16 / 26 / 19 MPG | 4,784 lbs | $109,800 |
| S560 Cabriolet | 4.6s | 13.1s | 463 | 516 | 4.0L Twin-Turbo V8 | 9-speed automatic | RWD | 17 / 24 / 19 MPG | 4,872 lbs | $109,800 |
| S560 Coupe | 4.5s | 13.0s | 463 | 516 | 4.0L Twin-Turbo V8 | 9-speed automatic | RWD | 17 / 26 / 20 MPG | 4,674 lbs | $109,800 |
| S560 Coupe | 4.5s | 13.0s | 463 | 516 | 4.0L Twin-Turbo V8 | 9-speed automatic | RWD | 17 / 26 / 20 MPG | 4,674 lbs | $109,800 |
| S500 4MATIC Sedan | 4.8s | 13.3s | 429 | 384 | 3.0L Turbo I6 | 9-speed automatic | AWD | 21 / 30 / 24 MPGe | 4,773 lbs | $109,800 |